A Review of Monkeypox: The New Global Health Emergency

Monkeypox, once a rare zoonotic disease, has been endemic to some African countries since its original identification among humans in 1970. Since then, cases non-endemic regions have linked returning travelers or those who had contact with transported animals. The causative agent, Monkeypox virus, belongs Orthopoxviruses, the same family as Variola—the organism for smallpox. Although most monkeypox outbreaks until recently were transmission, secondary human–human transmission smallpox-unvaccinated individuals was observed small proportion of overall cases. Smallpox declared be eradicated 1980, and eradication, virus significant poxvirus cause human disease. 2022 outbreak marks paradigm shift association, new modes concerns viral evolution entrenchment sexually transmitted clinically resembles smallpox but is far milder. At this time, there are no approved therapies monkeypox, antiviral agents effective against being utilized. Additionally, preventive strategies utilized include vaccinations such JYNNEOS ACAM2000. In narrative review, we discuss virology, epidemiology, clinical manifestations, diagnosis, management, prevention associated monkeypox.